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The Three Cs refer to a specific guideline regarding how medications are administered, particularly focusing on certain forms of medication. The correct answer highlights that the Three Cs apply to enteric-coated tablets and Spansules, which are designed to dissolve in specific conditions within the gastrointestinal tract.

Enteric-coated tablets have a protective layer that prevents them from dissolving in the stomach, allowing them to pass into the intestine before releasing their medication. This mechanism is essential for protecting the drugs from stomach acid or for ensuring that they are absorbed in the proper area of the digestive system.

Spansules are another type of capsule that contain time-release mechanisms. This means that they are formulated to dissolve and release their medication slowly over time, allowing for a prolonged therapeutic effect. Because of these formulations, proper adherence to the Three Cs is vital to ensure that the medication is effective and that the intended therapeutic outcomes are achieved.

Both enteric-coated tablets and Spansules require specific handling and administration techniques due to their unique properties, which is why they fall under the guidelines provided by the Three Cs.